Gastorgard is an oral paste used for the treatment and prevention of recurrence of equine gastric ulcers.
How GASTROGARD Works:
Omeprazole provides superior acid suppression because it most effectively shuts down acid production in the stomach, giving the ulcer time to heal. The cells of the stomach mucosa contain several acid-stimulating receptors, and when these receptors are activated they switch on the H+,K+ ATPase acid pump (an enzyme system) to secrete acid into the stomach. Omeprazole inhibits the acid pump, so when receptors are activated the acid pump does not initiate acid secretion. Omeprazole is the only medication approved for use in horses that acts directly on the acid pump, preventing acid secretion no matter what receptor is activated.
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